Don’t think so. I think it needs to be done via hooksecurefunc() but unfortunately Lua’s not my specialty.
https://warcraft.wiki.gg/wiki/API_hooksecurefunc
Something like
hooksecurefunc("CombatText_OnLoad", function(...)
COMBAT_TEXT_LOCATIONS = {startX = 200, startY = 400 * COMBAT_TEXT_Y_SCALE, endX = 200, endY = 600 * COMBAT_TEXT_Y_SCALE}
end)
But I’m not sure if that can just be done as above, or if it needs to be triggered via PLAYER_ENTERING_WORLD