No, those things might be somewhat rng (Affixes aren’t and tank routes 100% aren’t) but ultimately they’re things players are capable of handling and it’s the players actions that determine success.
RNG failure is your NPC tank dying because he didn’t use mitigation. No human was at fault, the game just chose not to do the mechanic.
I’m pretty certain some of the tanks I’ve gotten this week actually did use a RNG to produce their route. I got to experience killing all 4 gatekeepers in NW yesterday.