I am able to reliably reproduce the issue in Heroic Sludgefist (system details here). Somewhere in the beginning of the fight, it will freeze. If I quickly unplug the eGPU and replug it sometimes comes back, and I can continue the fight…if I don’t die. Which is really not ideal in progression.
Here are the logs in case what happened up until my deaths are helpful: https://www.warcraftlogs.com/reports/7LBkT9v3fgyWbntX/#boss=2399&difficulty=4&wipes=1
I was present for wipes 1-4 before I sat myself for being a liability. I can also get system logs if needed.