What is the best 5 dps + X comp

I would say Ana.

Ana can heal from long range. It’s good in a 5 dps game where those dps are usually splitted.

Moira is just horrible : you past your time running at some allies, while the other ones die.
And when you dare to have a little fun, or recover your heath-charge, you get called a dps moira.

Zen is, like ana, really good. It’s easy to heal with your orbs to these 5 dps.
But you don’t have the burst heal ana can have (but you don’t have to aim)

Mercy : i don’t know i never played that hero.

Lucio : Same like Moira’s case. When all your DPS are usually splitted it’s not revy effective.