Settings are kinda personal preference for many things.
But use a wired mouse if you can.
My DPI/Sens is 800/3.51
I play at 1080p 240hz
and I use the same sens for all the heroes many people switch them up for tanks and genji
As far as video settings mine are here
vsync = off
triple buffering = off
reduce buffering = on
and I display my fps and ping
