- Mercy + Lucio
Mercy: “I’m curious about your music Lucio. I’ve heard music helping patients relax but never actually healing them.”
Lucio: “To be honest, Doc, you understand that as well as me.”
- Sombra + Reinhardt
Sombra: “Are you ever going to tell Brigitte the truth?”
Reinhardt: “You should learn when to shut your mouth.”
Sombra: “As soon as you do. I think I’ve got a few years.”
- Orisa + Lucio
Orisa: “What is this Vishkar?”
Lucio: "An evil that wants to constrict freedom.
- Orisa + Symmetra
Orisa: “What is this Vishkar?”
Symmetra: “A company paving the way to a brighter future.”
- Moira + Wrecking Ball
Moira: “You must let me study your genetic therapy, Hammond. The Horizon Colony’s notes were hazy on many details.”
Wrecking Ball: -Squeaks- “ERROR: Profanity filter is enabled. Cannot translate.”
- Wrecking Ball + Wrecking Ball
Wrecking Ball: -Squeaks- “WARNING: Likelihood of temporal instability increasing.”
Wrecking Ball: -Squeaks- “He concurs.”
- Wrecking Ball + Winston
Wrecking Ball: -Mournful Squeaks-
Winston: “I know, Hammond. I miss him too.”
- Bastion + Wrecking Ball
Bastion: -Deeply Philosophical Conversational Beeps-
Wrecking Ball: -Deeply Philosophical Responsive Squeaks-
- Pharah + Junkrat
Pharah: “‘Explodey?’ Are you serious?”
Junkrat: “Do I look serious to you?”
- Sombra + Soldier: 76
Sombra: “Gracias for saving Alejandra. I may not seem like it but I care for the people of Mexico.”
Soldier: 76: “Didn’t expect to hear something like that coming from you.”
- Wrecking Ball + D.Va
Wrecking Ball: -Squeaks- “He wishes to know more about the Fusion Reactor Core installed into your mech.”
D.Va: -Giggles- “You might wanna ask Dae-Hyun about that one.”
EDIT: Decided to add some more!
Torbjorn + Brigitte
Torbjorn: “I thought I told you to leave that cat alone.”
Brigitte: “But haven’t you ever wanted to see him soaring through the sky on a Jetpack, Papa?”
Torbjorn + Ana (Suggested by LancerJayden)
Torbjorn: “It’s hard to believe our little girls are out here on the battlefield.”
Ana: “They’re all grown up now and we can’t stop them, all we can do is be there for them.”
Symmetra + Mcree
Symmetra: “It’s High Noon?”
Mcree: “Y’ seem a bit confused there.”
Symmetra: “Well see, I don’t understand why people keep asking me.”
Lucio + Widowmaker:
Lucio: "Woo! The party don’t stop 'til I do!
Widowmaker: “That can be arranged.”
Ana + Moira:
Ana: “You knew no restraint, Moira. Overwatch had to shut you down.”
Moira: "Pssh. Of course the old hag would want to slow down progress.
Moira + Ana:
Moira: “Oh, it’s you. Aren’t you missing your wheelchair, Grandma?”
Ana: “I can walk just fine. However you seem cranky, perhaps you need a nap.”
Junkrat + Wrecking Ball:
Junkrat: “The Champion of the Scrapyard is… a Hamster? I didn’t take a whiff of that Hogdrogen stuff again, did I?”
Wrecking Ball: -Squeaks- “He said he’d be happy to sign an autograph.”
DOUBLE EDIT: Got asked for Roadhog interactions, so take this one and another. 
D.Va + Roadhog
D.Va: “Hey, Roadhog. You’ve got me… hooked. Hehe.”
Roadhog: “And I thought no one was more annoying than him.”
Widowmaker + Reaper:
Widowmaker: “Why do you insist on wearing that ridiculous outfit?”
Reaper: “It fulfils its purpose. To hide the monster underneath.”
