Howdy!
Can you try enabling High Precision Mouse Input found under Gameplay Options. See if that helps you out! 
If the issue continues we would want to know what kind of mouse you are using? Along with getting a screenshot of your Network Graph toggled by using (Shift+Ctrl+R). Along with your network graph we would want to see your performance stats at the time of the issue: Goto Options → Video → Toggle Display Performance Stats to on. Under: Advanced Performance stats turn everything on.
Take the screenshot when the issue occurs, upload it to a site like Imgur.com → Link it back here within the code below:
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`Link Here`
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Thanks!