It depends on your disability. But, there are a fair number of us who are concerned for this precise reason.
Personally, I have an issue that makes it physically painful to play most of the roster, and I can’t play them very effectively because my muscles don’t cooperate much of the time. Symmetra is the only character that both doesn’t hurt nearly as much, and has an entire character design that does not require fast reflexes and has more forgiving aim (due to her DOT primary fire).
But, with the kit changes, I (and other’s like me) will no longer be able to play her, which means I won’t get to play Overwatch much, if at all.
The sad thing is the community response since a handful of us have tried to bring attention to this on various forums in the hope that Kaplan and company will spare 1/27th of the hero roster for game accessibility. Aside from a wonderful few who are trying to raise awareness or show support, most Normies usually:
A) list other characters and say play them*
B) point at a single member of the disabled community and imply/declare that if that one person with that specific disability and rig can do it, clearly everyone else can
C) or basically just tell us we’re not worth paying attention to because they don’t think there are enough of us to be considered important
It’s a shame, really. And a poor business move as they’re closing themselves off from a sector of the market.
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*This is usually the first thing everyone says to me, and to head off any replies, I’ll just recycle an old comment:
"People tend to think this a lot, but the issue goes further than one aspect of the kit.
…
As for all the heros everyone usually recommends to replace her, they don’t quite mesh up, as most of them are only superficially accessible. While they all require minimal aiming for their primary fire (or Torb’d turret), most of the remainder of their kit relies on fast reflexes and reliable muscle movement in order to use them even somewhat effectively.** Having them act as a replacement for Sym, isn’t the same.
**For those thinking, ‘Just don’t use those portions of their kits then.’: That’s like telling someone to play the game while under a perpetual Sombra Hack. Not exactly a fun prospect, is it?"