I actually wouldn’t be surprised if Blizzard nerfed Zenyatta’s Orb of Harmony to only work within 20 meters or something of the sort.
Lucio really got hurt once his radius was shrunk to where it is now, which in turn really hurt Ana considering that she used to get healed with his enlarged radius.
Ana currently doesn’t have synergy with any of the Supports considering that assisting her limits their effectiveness.
All of the other Supports have to work within range of their team, which makes it easier for their teammates to peel, meanwhile, Ana being in the up close is asking for her to die whilst sitting in the back is also asking for her to die as well and unlike Zenyatta, Ana doesn’t have a Discord Orb that allows her teammates to quickly get rid of the teams attacking her.
Meanwhile, Moira actually synergizes a lot better with Lucio since they’re both restricted to short-range healing…but having limited range with your healing is a very big downside to manage.
Brigitte is in a weird state where she takes up a DPS slot rather than a Support slot, and while in theory, she should synergize well with Ana (due to her larger healing radius 20 meters vs. Lucio’s 10 meters) her need to be more in the thick of it makes their synergy pretty weak.
As it stands, Support synergy is mostly:
Mercy / Zenyatta
Moira / Lucio
Mercy / Zenyatta / Brigitte