I have all the latest video and system drivers. A few minutes after playing, the whole system crashes and the cooling fans start running following the shutdown, Basic system specs are as follows:
AMD Ryzen 9 9900X 12-Core Processor (4.40 GHz)
32.0 GB (31.1 GB usable) RAM
NVIDIA GeForce RTX 5080
I have the same problem here. Had this also in season 11 already, but way less frequent.
Some the game crashes already in the menu.
And I am pretty sure it causes the RTX 5080 to shut off or something, because I can also see the light of the GPU switches off. Screens go darf and after a while the PC restarts. Sometimes it takes two restarts for the display to come back.
Temperatures of the GPU are just fine, even right before the crash it wasn’t higher than 70°C.
I have the AMD 9800x3d the RTX 5080 (FE) and 64 GB of RAM.
Yeah, I am having same problem, all other games are running perfectly fine, only D4 hard sound issue and massive lag, then crash! All my drivers and hardware are fine, I had no problem in S11, now S12 this problem is back, I even tried different (clean) drivers.
Blizzard wake up!
The game is completely unplayable for me. Even if I get in without a crash, anything I do hangs the game. Honestly amazed that this would happen with a new season…
Is it crashing when you teleport, or even just sitting idle in town?
The teleport issue is known and supposedly Blizz is working on it.
Same thing happened to me just now. The game went down and locked up my computer. Had to do a hard reboot. Please fix the dang game and stop being LAME! With all the complaints about the game crashing I would think that you would make it a TOP priority getting it FIXED. If your people can’t fix it than I would say “IT’S TIME TO GET A NEW CREW WHO CAN FIX IT AND MAKE IT A QUALITY GAME.” But thats just my opinion! 
If it’s the black screen thing, provide logs to help them troubleshoot. It’s been outstanding for over a year (really since D4’s launch), so they’re hardly making it a “TOP” priority, but they are asking for logs at least, after months and months of the issue -
Mine isnt a black screen thing, its a says its loading and then nothing. Doesnt load.
Same thing for me plus I get a locked computer 
Happy to say this season will be over because Season 12 is the WORST ever! Between this problem and NOT BEING ABLE TO UPGRADE my stuff season 12 sucks!
Still happening. I thought I had fixed it, but it has come back. What an annoyance.
Just bought it, because poe2 patch is a month away, and Im done in poe 1 with 20+ mirrors.
And said why not, I heared a lot of good things about this season, Im sure they fixed the game that I paid more than 100 euros in total to play…
But sadly, I cant even log in after the prepatch dl, wow blizz…
So many years and you are still at this point, honestly, get your **** together someday…
Imagine what we will see on launch day…
I feel like I’m waiting for this pile of game to unfreeze more than I’m playing it.
It only happens with this trash game.
same here and only with d4.
Its unplayable. and i have nothing changed at my system. i de and reinstalled, verified the files and so on.
nothing works. and they are maybe server issues to? the response time when i try to open the map takes very long or the game crashed.
and there is no support any more in the forum? Good Job Blizz and Microslop.
i cant play a game anymore for what i paid over 100€? Yea thats nice.
Nothing to do with M$. 
It’s 99% a blizzard failure, and maaaaaybe 1% AMD, since those players with crash and teleport issues typically have an AMD GPU. In the D4 development, Blizz definitely focused almost exclusively on NVDA and Consoles, since that’s what the majority of the users play on.
They’ve left those with AMD GPUs totally in the cold with no recourse other than to use 3rd party CPU limiters like BES to try work around the inherent issues with D4.