ehhhh. Once is enough for me, unless the side actually has random progress regardless. Like the exorcism side, You could have succeeded in saving the child, but at the end of it you failed to exorcise the priest, and have to slay her.
If it is the same stuff every time, I tend to do the bare min for the renown and bounce to the next thing.
The npc can stand there and praise dust and rolling tumbleweeds.