Never ever assume its a 0 chance.
That is a driver/hardware error. Caused either by a software conflict in the driver, or a hardware fault.
Is that card crashing?
BTW.
Have you thought about clearing the LocalPrefs file from the Documents\Diablo IV folder? Especially if you played in beta/slam? It is not removed or updated from those times, and might cause setting problems. Of course they haven’t said as much, but a simple rename of the file and reopen of the game creates a new default settings file.
I love how instead of playing the game as defaulted when installed and making sure it plays ok, everyone wants to crank it to Ultra then don’t understand why its having issues.
I know its frustrating when these things happen.
But just because you think it is something else, doesn’t mean its something else. But don’t get me wrong here. I am not putting Blizzard off the hook either. There are issues in play and they have more work to do, but they cannot physically damage the card with the game. There has to already been a problem in order to have it show up.
Is the game optimized and running well on various cards? No. I just spent time on another thread doing a simple 10 minute standing in place test at the armor vendor. It makes the card run hotter than if you are running around on the map fighting monsters. So yeah, they have issues. But their software can’t just damage hardware. It can however stress the card to the point where something will give.
Anyway. Good luck.