Barbarian has the Primary skills weapon sanctified and saved in the closet. When equipped from the closet, the sanctified weapon is skipped as if it were missing. This has and could lead players not noticing the glitch to start and lose grifts they could otherwise win. It took me 3 grifts before I noticed that the weapon wasn’t equipped. This is easily reproduced. Sanctify any weapon, equip in the primary slot, save in the closet then unequip and try to equip from the closet.
This happens when you try to switch builds and you have sanctified gear in a different slot.
The restriction that only one sanctified item can be equipped prevents you from equipping the new item until you have removed the other one.
If you click the “equip” button twice it will work because at that point you’ll no longer have any other sanctified item equipped.
I don’t think they’ll change it because it could introduce some bug that lets people equip multiple sanctified pieces through the armory.