Hello Blizz, I know this is an old topic but I cant seem to resolve the problem of the game freezes for 5 seconds in-game. I have already uninstalled and installed the game but still same problem. Please help me because I cant enjoy the game specially when im pushing higher greater rifts or just normal playing…
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Thanks for posting this thread, I am having the same issue as you. 
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Same problem after updating the AMD driver for my 5700xt (latest driver) I get random 5 second or longer freezes during games.
I now believe the issue is due to the windows 2004 update
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See this topic
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