Barbs are great for this, but keep in mind: Ubers are designed to force you into maximizing your builds. It’s the elite end game goal, not a jack of all trades farming spot.
That being said, a Barb can do everything in the game with the right setup. My IK barb with dual Ali Baba’s and a helm with Ptopaz has around 320% MF, and that’s without any MF on his rings or ammy. He can also solo anything in the game, except possibly ubers (that would take a great deal of work with his off-set slots and merc, which I don’t want to do). But I’ve seen it done.
So any main skill for a barb will work fine if you can get gear setups for it. I have preference for WW, but if your aiming for Ubers, Frenzy or Dual swing with Zerk may be an easier path.
basic setup would be: max main skill and synergies, max BO, max weapon specialty of choice, 1 pt in everything else. Extra points can go in areas that will help you kill faster. shout boosts beserk, so it can help to dump extra points there.
general use gear would revolve around crushing blow, critical strike, and AR: you need allot to hit in Hell. you’ll need mana and life leech.
MF gear: Dual Ali baba’s on switch for kill and horking. Ik helm with Ptopaz, nagelring, etc. The challenge with an MF barb is you have to sacrifice offensive and defensive stats for MF. IK set is great for this, since it adds roughly 85% MF in the set itself, but it’s tailored for WW or Concentrate build.
If you want a Grushing king, you’ll want Enigma, though I do my own Grushes with the IK barb and no issues, just slower.
Concentrate is your boss killer, Beserk is for Phys immunes. War Cry is optional, but I find that a point in it can help control mobs. prestigious use of howl and grim totem can help control mobs as well, so they’re mandatory 1 pointers too.